The ability to regenerate organ and limbs is a covetable skill held by some member of the animal kingdom . Lizards are famous for theirtail growingskills ( and sometimes grow backmore than one ) whilealligatorsrecently joined the club as it was found they too can regenerate a lose fanny . alas , it ’s a skillset humans are without ( unless you count thatlizard guyfromSpiderman ) but it ’s the focus of much inquiry hoping to one day harness its mechanisms for exercise in human medicine , better recuperation sentence , and reducing complications that often play along incursive surgeries .
One radical of mice are fast emerge as an exciting inquiry organism due to their remarkable power to undergo scarless positive feedback of complex tissues including skin and skeletal muscle . A Perspective article bring out in the journalNPJ Regenerative Medicinedetails the incredible re-formation power of the spiny mouse ( genusAcomys ) , which show scar - gratuitous healing while also partake in some physiological process with mankind , making them a hopeful candidate for translatable insights .
When you prune your hand , your skin is n’t capable to rejuvenate itself and so instead the lesion is sealed with slow scar tissue through fibrosis , an umbrella term for the process that forms scar tissue . Fibrosis can sometimes work against us , causing complications in multiple Hammond organ , which can be deadly and account for around 45 percent of all death in the United States , according to the newspaper ’s author . It ’s hoped that through the growth of regenerative medicine , Dr. could one Clarence Shepard Day Jr. replace and restore damage tissue paper and remove the suffering stimulate by fibrosis - related conditions .
Studies have investigated a variety of spiny mouse tissues to see how well they can regenerate , and the resolution prove that this specie is a select competitor forregenerative medicine . study have shown at least threeAcomysspecies can fully regenerate and regrow complex tissues , admit removed ear tissue , damage kidney tissue paper , and even recovering from injury to the heart . While the accurate mechanisms behind these regenerations have not yet been isolate , it ’s hoped future inquiry could barrack novel therapeutic approaches for patients with enfeeble sickness .
Acomysis particularly exciting for human medicine as they are screw to exhibit human - like physiologic characteristics that are rare in rodents including menses , acquired diabetes ( from a high-pitched - avoirdupois or gamey - carbohydrate diet ) , and the yield of steroid hormone internal secretion . These similarities paint a bright impression that insights gleaned from the enquiry of these fauna could one day be translate for effective use in humans .
